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Outcomes and prognosis news

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Side-effects
Tenofovir impairs enzyme that stops cells ageing

A team of Australian researchers has found that tenofovir and, to a lesser extent, other drugs from the nucleoside/nucleotide reverse transcriptase inhibitor (NRTI) class, impairs an enzyme that

Published
31 January 2013
By
Gus Cairns
Hepatitis C symptoms and diagnosis
Spanish research shows that liver stiffness can predict outcomes in people co-infected with HIV and hepatitis C

Liver stiffness is a strong predictor of hepatic complications and all-cause mortality in people co-infected with HIV and hepatitis C virus (HCV), Spanish investigators report in the

Published
30 January 2013
By
Michael Carter
Outcomes and prognosis
Mortality rates continue to fall in the Swiss HIV cohort

Mortality in people with HIV is continuing to fall, Swiss investigators report in HIV Medicine. The mortality rate in 2010 was a little over 1% and the

Published
25 January 2013
By
Michael Carter
Outcomes and prognosis
Australian researchers project that many HIV-positive people will run out of treatment options

Running out of antiretroviral treatment options may severely curtail the life expectancy of people with HIV in resource-rich countries, according to Australian research published in

Published
22 January 2013
By
Michael Carter
Resistance
Prevalence of drug-resistant HIV has fallen dramatically among antiretroviral-experienced patients in Western Europe

There has been a significant fall in the proportion of HIV-positive people in Western Europe with experience of HIV treatment who have resistance to antiretroviral

Published
22 January 2013
By
Michael Carter
Side-effects
Large study shows the hepatic safety of HIV therapy

Results from a large study published in the online edition of Clinical Infectious Diseases provide reassurance about the hepatic safety of antiretroviral drugs. Investigators from the D:A:D study

Published
22 January 2013
By
Michael Carter
Smoking
Smoking has a bigger impact on the prognosis of HIV-positive patients than HIV-related factors

Much of the increased mortality seen in patients with HIV can be attributed to smoking, Danish investigators report in the online edition of Clinical Infectious Diseases. “The loss

Published
31 December 2012
By
Michael Carter
Outcomes and prognosis
Poor CD4 response to HIV treatment increases risk of death from non-AIDS-related illnesses, even for those with higher baseline counts

A poor increase in CD4 cell count after starting antiretroviral therapy is associated with an increased risk of death due to non-AIDS-related causes, Danish investigators report in

Published
28 December 2012
By
Michael Carter
Outcomes and prognosis
HIV patients in care lose more years of life to smoking than to HIV infection

Among HIV patients receiving well-organized care with free access to antiretroviral therapy, those who smoke lose more years of life to smoking than to HIV, according to a Danish study published in Clinical Infectious Diseases and available online.

Published
21 December 2012
From
EurekAlert
Nutrition
Diet quality predicts HIV progression and death in resource-poor settings

The more diverse and nutrient-rich the diet before starting antiretroviral treatment (ART), the less severe HIV disease progression is, and the less likely death occurs, researchers report in

Published
06 December 2012
By
Carole Leach-Lemens
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